THE
23rd ANNUAL MEETING OF THE JAPANESE SOCIETY
FOR BIOMEDICAL MASS SPECTROMETRY
| FINAL PROGRAM |
September 24 (Thur.)-26 (Sat.),
1998
KANAZAWA CITY BUNKA HALL
15-1, Takaoka-machi, Kanazawa
TEL : 076-223-1221
President of the 23rd Annual Meeting
Tomiko Kuhara, Ph.D
Division of Human Genetics, Medical Research Institute
Kanazawa Medical University
| Sept.24(Th.) | 09 : 00 Registration 09 : 00 Meeting of the Board of the Directors 09 : 55 Opening Remarks 10 : 00 Scientific Sessions (oral communication) 12 : 24 Lunch 13 : 30 Scientific Sessions (oral communication) 14 : 20 Invited Lecture I
|
| Sept.25(Fr.) |
09 : 00 Scientific Sessions (oral communication) 10 : 36 Symposium II:
13 : 30 Meeting of the JSBMS Members 14 : 20 Invited Lecture II
|
| Sept.26(Sat.) |
09 : 00 Scientific Sessions (oral communication) 09 : 50 Invited Lecture III
12 : 30 Closing Remarks |
| 9 : 55 | Opening Remarks Tomiko Kuhara, President
of the 23rd JSBMS meeting |
| 10 : 00 | Oral Communication Chairpersons: Osamu Suzuki, Noriko Kakuda A fatal intoxication case due to DDVP ingestion - with reference to DDVP concentrations in the blood, urine and organ tissues T. Takayasu, T. Ohshima, T. Kondo, M. Ohtsuji (Dept. of Legal Med., Kanazawa Univ. Faculty of Med., Sch. of Med.) Analysis of abused drugs by surface ionization mass spectrometry (SIOMS): Identification and sensitive quantitation of phencyclidine A. Ishii1, H. Seno1, K. Watanabe-Suzuki1, F. Guan1, H. Matsushima2, H. Hattori3, O. Suzuki1 (1Dept. of Legal Med., Hamamatsu Univ. Sch. of Med., 2Dept. of Environ. Sci., Hamamatsu Univ. Sch. of Med., 3Dept. of Legal Med., Aichi Med. Univ.) Toxicological analysis of pentazocine in human tissues by liquid chromatography/fast-atom-bombardment mass spectrometry T. Imamura1, K. Kudo2, M. Yashiki1, T. Kojima1 (1Dept. of Legal Med., Hiroshima Univ. Sch. of Med., 2Dept. of Forensic Med., Faculty of Med., Kyushu Univ.) Rapid screening of bromovalerylurea poisoning by direct inlet FAB-MS M. Sagi, K. Yamazaki (Dept. of Legal Med., St. Marianna Univ. Sch. of Med.) |
| 10 : 48 | Oral Communication Chairpersons: Toru Kojima, Keiko Kudo Forensic diagnosis of brain death by analyzing drug distribution in human tissues K. Kudo1, N. Ikeda1, Y. Hino1, T. Imamura2 (1Dept. of Forensic Med., Faculty of Med., Kyushu Univ., 2Dept. of Legal Med., Hiroshima Univ. Sch. of Med.) Analysis of ethyl glucuronide, a minor metabolite of ethanol, by electrospray - LS/MS M. Nishikawa, H. Tsuchihashi (Forensic Sci. Lab., Osaka Pref. Police H.Q.) Analysis of eight phenothiazine derivatives with long side chains by HPLC/MS/MS H. Hattori1, H. Seno2, A. Ishii2, T. Yamada1, O. Suzuki2 (1Dept. of Legal Med., Aichi Med. Univ., 2Dept. of Legal Med., Hamamatsu Univ. Sch. of Med.) HPLC-APCI-MS determination of anticoagulant rodenticides by using an ion- pairing reagent F. Guan, A. Ishii, H. Seno, K. Watanabe-Suzuki, O. Suzuki (Dept. of Legal Med., Hamamatsu Univ. Sch. of Med.) |
| 11 : 36 | Oral Communication Chairpersons: Akira Hayashi, Fumio Inoue Mass spectrometric analysis of 17-ketosteroid in urine stain T. Hisatomi, T. Nakazono, Y. Hayashiba, S. Fukushima (Forensic Sci. Lab., Fukuoka Pref. Police H.Q.) Analysis of cholesterol hydroperoxides in fatty liver using high-performance liquid chromatography/mass spectrometry J. Adachi, M. Asano, Y. Ueno, H. Nushida, Y. Tatsuno (Dept. of Legal Med., Kobe Univ. Sch. of Med.) Separatory determination of bile acid 24-glucuronides by LC/ESI-MS H. Okuyama, N. Murao, S. Ikegawa, J. Goto (Faculty of Pharm. Sci., Tohoku Univ.) Simultaneous determination of four human female steroid hormones in blood by mass fragmentography A. Hayashi1, J. Kitatani1, M. Aoki1, K. Teramoto1, K. Nakashima1, Y. Aritomi1, Y. Takata1, M. Morita2 (1Kansai Lipid Inst., 2Joint Res. Center, Kinki Univ.) |
| 12 : 24 | Luncheon |
| 13 : 30 | Oral Communication Chairpersons: Masaki Takayanagi, Toru Obata Simultaneous analysis of prostaglandins and thromboxane in the cerebrospinal fluid by GC/MS T. Obata1, T. Nagakura2, H. Maeda2, K. Yamashita3, K. Maekawa2 (1Div. of Molecular Cell Biology, Inst. of DNA Med., Jikei Univ. Sch. of Med., 2Dept. of Pediatr., Jikei Univ. Sch. of Med., 3Res. Lab. of Pharm. Group, Nippon Kayaku Co., Ltd.) Application of DE MALDI-TOF/MS to analysis of sphingolipids in tissues from sphingolipidosis patients T. Fujiwaki1, S. Yamaguchi1, K. Sukegawa2, T. Taketomi3 (1Dept. of Pediatr., Shimane Med. Univ., 2Dept. of Pediatr., Gifu Univ. Sch. of Med., 3Dept. of Biochem., Res. Center on Aging and Adaptation, Shinshu Univ. Sch. of Med.) Trimethyllysine analysis by liquid SIMS/MS: Interference by homoarginine N. Terada1,2, M. Okochi3, H. Nakajima4, Z. Kizaki2, A. Kinugasa2, T. Sawada2, F. Inoue5 (1Hananoki Med. and Welfare Center, 2Dept. of Pediatr., Kyoto Pref. Univ. of Med., 3Dept. of Pediatr., Aonogahara Hosp., 4Dept. of Pediatr., Shakaihoken Kyoto Hosp., 5Kyoto Univ. of Education) Effect of sports activity on carnitine metabolism F. Inoue1, N. Terada2, K. Nakajima2, M. Okochi2, N. Kodo2, A. Kinugasa2, T. Sawada2 (1Dept. of Sch. Health, Kyoto Univ. of Education, 2Dept. of Pediatr., Kyoto Pref. Univ. of Med.) |
| 14 : 20 | Plenary Lecture Chairperson: Masakatsu Sudo Radical Thoughts about Phospholipid Oxidation: New Directions for Mass Spectrometry Prof. Robert C. Murphy (National Jewish Center for Immunology and Respiratory Medicine) |
| 15 : 20 | Break |
| 15 : 30 | Symposium I New Trends in the Mass Spectrometry of Biopolymers Chairpersons: Yoshinao Wada, Takekiyo Matsuo 1. An approach to the characterization of bioactive natural products using mass spectrometry H. Naoki (Suntory Inst. for Bioorganic Res.) 2. Structural analysis of a protein by FT-ICRMS ŽÐ Advantages of 13C, 15N -doubly depleted protein in fragment identification - S. Akashi1, K. Takio1, H. Matsui2, S. Tate2, M. Kainosho2 (1Div. of Biomolecular Characterization, The Inst. of Phys. and Chem. Res. (RIKEN), 2Faculty of Sci., Tokyo Metropolitan Univ.) 3. Proteion structure changed by genetic mutation or post-translational modification, 5 new finidngs M. Kishikawa, T. Nakanishi, A. Miyazaki, A. Shimizu (Dept. of Clin. Pathology, Osaka Med. College) 4. Counting the number of triplet repeats by MS Y. Wada1, O. Ogawa2 (1Osaka Med. Center and Res. Inst. for Maternal and Child Health, 2Dept. of Urology, Akita Univ. Sch. of Med.) |
| 9 : 00 | Oral Communication Chairpersons: Ichirou Yoshida, Toshihiro Shinka Screening urine of 5-day-old newborns: Metabolic profiling of neonatal galactosuria T. Shinka, H. Peng, Y. Inoue, T. Kuhara (Div. of Human Genetics, Med. Res. Inst., Kanazawa Med. Univ.) Urinary excretion of galactonic acid in neonates with hypergalactosemia N. Sakura (Dept. of Pediatr., Hiroshima Univ. Sch. of Med.) A case with b-ketothiolase deficiency A. Miyazaki1, T. Nakanishi1, M. Kishikawa1, A. Shimizu1, A. Inoue2, M. Mino3 (1Dept. of Clin. Pathology, Osaka Med. College, 2Dept. of Pediatr., Saiseikai Ibaraki Hosp., 3Seikeikai Hosp.) Tissue specificity in amino acid conjugation of carboxylic acids F. Kasuya, M. Hiasa, K. Igarashi (Faculty of Pharm. Sci., Kobe-gakuin Univ.) |
| 9 : 48 | Oral Communication Chairpersons: Tomokazu Suzuki, Seiji Yamaguchi Urinary excretions of organic acids in premature infant M. Takayanagi (Dept. of Pediatr. Chiba Children's Hospital) Screening for fatty acid beta oxidation disorders: Acylglycine analysis using stable isotopes by gas chromatography-mass spectrometry M. Kimura1, S. Yamaguchi1, Piero Rinaldo2 (1Dept. of Pediatr., Shimane Med. Univ., 2Dept. of Genetics, Yale Univ. Sch. of Med.) 3-deoxyglucosone in erythrocytes from hemodialysis patients with diabetes mellitus S. Tsukushi1, C. Naito1, I. Aoyama1, F. Takayama1, M. Kajita2, T. Miyazaki1, T. Niwa1 (1Dept. of Clin. Preventive Services, Nagoya Univ. Daiko Med. Center, 2Dept. of Pediatr., Nagoya Univ. Med. Sch.) The re-evaluation of Hb A1c values and characterization of a new variant hemoglobin by ESIMS T. Nakanishi, A. Miyazaki, M. Kishikawa, A. Shimizu (Dept. of Clin. Pathology, Osaka Med. College) |
| 10 : 36 | Symposium II Mass Screening and Chemical Diagnosis of Metabolic Disorders in Asian Countries Chairpersons: Isamu Matsumoto, Shoichi Sakamoto 1. Introduction: Study of metabolic disorders in Asian countries - The significance and role of collaboration S. Sakamoto (Aiiku Maternal, Child Health & Welfare Center) 2. Inborn errors of metabolism discovered at Centre for Research in Mental Retardation (CREMERE) in India Usha P. Dave (Centre for Research in Mental Retardation; CREMERE) 3. Inborn errors of metabolism in Bangkok, Thailand Pornswan Wasant (Siriraj Hospital, Mahidol University) 4. Studies on inherited metabolic diseases in Shengyang, China Guizhang Dong (Department of Pediatrics, The First Hospital, China Medical University) 5. Pilot study report: Application of chemical diagnostic procedure by GC/MS to newborn mass screening T. Kuhara (Div. of Human Genetics, Med. Rese. Inst., Kanazawa Med. Univ.) 6. Conclusion I. Matsumoto (MILS Co., Ltd.) |
| 12 : 30 | Meeting of the Board of Trustees |
| 13 : 30 | Meeting of JSBMS Members |
| 14 : 20 | Plenary Lecture II Chairperson: Susumu Nishimura Mass Spectrometry and the Proteome: New Approaches to Deciphering Protein Function Prof. John R. Yates (Molecular Biotechnology, School of Medicine, University of Washington) |
| 15 : 20 | Break |
| 15 : 30 | Symposium III New Development in the Application of Mass Spectrometry to Clinical Medicine Chairpersons: Kenji Maeda, Makoto Yoshino 1. Characterization of peptides bound to the class I MHC molecule using nano-LC/MS/MS N. Yamada1, M. Suzuki1, J. Hamuro1, Y. Chujo1, K. Miwa1, H. Sahara2, N. Takahashi2, N. Sato2, K. Kikuchi2, M. Takiguchi3, H. Tomiyama3, K. Hirayama1 (1Central Res. Lab., Ajinomoto Co., Inc., 2Sapporo Med. Univ., 3Kumamoto Univ.) 2. Electrospray tandem mass spectrometry for neonatal screening using blood spots of Guthrie paper Y. Shigematsu1, Y. Tanaka2, M. Sudo3 (1Dept. of Pediatr., Fukui Med. Univ. Hosp., 2Central Res. Lab., Fukui Med. Univ., 3Fukui Med. Univ.) 3. Mass spectrometric study on modification of protein or lipids in uremic patients H. Odani1, Y. Matsumoto1,T. Shinzato1, M. Mune2, J. Usami1, Kenji Maeda1 (1Dept. of Internal Med., Daiko Med. Center, Nagoya Univ. 2Dept. of the Third Internal Med., Wakayama Med. College) 4. Application of GC/MS analysis of urinary sugar and sugar-alcohols to the clinical management of pregnant woman with abnormal carbohydrate metabolism M. Tetsuo1, H. Matsumoto2, C. Zhang3, I. Matsumoto3 (1Tetsuo Hosp., 2Nippon Red Cross Hosp. at Kanazawa, 3MILS Co., Ltd.) |
| 18 : 00 | Banquet |
| 9 : 00 | Oral Communication Chairpersons: Junichi Goto, Toshimitsu Niwa Determination of 1-methyl-TIQ in mouse brain after treatment with haloperidol by GC/SIM system K. Igarashi1, Y. Sugiyama1, F. Kasuya1, S. Ohta2 (1Biochem. Toxicology Lab., Faculty of Pharm. Sci., Kobe-gakuin Univ., 2Inst. of Pharm. Sci., Hiroshima Univ. Sch. of Med.) Characterization of a mutant hemoglobin by genetic and protein analyses R. Kaneko1, T. Matsuo1, Y. Wada2 (1Dept. of Physics, Graduated Sch. of Sci., Osaka Univ., 2Res. Inst. Osaka Med. Center for Maternal and Child Health) Glutathionyl hemoglobin in uremia C. Naito1, S. Tsukushi1, F. Takayama1, I. Aoyama1, M. Kajita2, T. Miyazaki1, T. Niwa1 (1Dept. of Clin. Preventive Services, Nagoya Univ. Daiko Med. Center, 2Dept. of Pediatr., Nagoya Univ. Med. Sch.) Early detection of extrahepatic biliary atresia by tandem mass spectrometry I. Mushtaq1, M. Morris2, P. Clayton1, A. Johnson1, S. Logan1 (1Inst. of Child Health, 2Micromass UK Ltd.) |
| 9 : 50 | Plenary Lecture III Chairperson: Akira Shimizu Mass Spectrometry of Opioid Peptides, Proteins, and Enzymes Prof. Dominic M. Desiderio (Dept. of Neurology and Biochemistry, Charles B. Stout Neuroscience Mass Spectrometry Laboratory, University of Tennessee) |
| 11 : 00 | Workshop Information on New Instruments Chairpersons: Shigeki Daishima, Hidenori Kizawa 1. The latest application using benchtop Shimadzu LCMS-QP8000 H. Kubo, H. Murata, S. Kawano, S. Yamaki, M. Hayashi (HPLC Business Dept., Shimadzu Corporation) 2. Analysis of bile acid 3-glucronides by using benchtop high resolution LC/MS system "JMS-LCmate" Y. Takahashi1, T. Morita1, T. Higuchi1, J. Goto2 (1Application and Res. Center, Analytical Instrument Div., JEOL Ltd., 2Faculty of Pharm., Tohoku Univ.) 3. Speciation of arsenic compounds in the urine of rats orally exposed to dimethylarsinic acid by LC-ICP-MS Y. Inoue1, Y. Date1, T. Sakai1, N. Shimizu1, K. Yoshida2, H. Chen2, K. Kuroda2, G. Endo2 (1Div. of R&D, Yokogawa Analytical Systems Inc., 2Dept. of Preventive Med. and Environ. Health, Osaka City Univ. Med. Sch.) 4. New instruments of LC/MS/MS mass spectrometer, PE-SCIEX API2000 and API3000 Takashige Kanda (Biomedical Sales Sec., Takara Shuzo Co., Ltd.) 5. Identification of proteins using an ion trap mass spectrometer - LCQ R. Kiyonami1, M. Kubota1, Y. Maeda1, H. Ikezawa1, A. land2 (1ThermoQuest K.K., 2Finnigan) 6. Introduction of platform LCZ system featuring Z-Spray API interface N. Isobe, J. Yonekubo, M. Kanai (Nihon Waters K.K.) 7. The application of automated exact mass measurement with the Micromass LCT ESI-TOF for combinatorial chemistry M. Morris1, D.Daley2, J. Hoyes1, S. Jarvis1, J. Letcher1, D. Little1, R. Scammell2 (1Micromass UK Ltd., 2Rhone Poulenc Rorer) |
| 12 : 35 | Closing remark |
Last updated on August 11, 1998
